Lee, N., Han, S. M., Mukadi, P., Edwards, T., Maung, H. T., Smith, C., & Win, T. Z. (2025).
Corticosteroids for treatment of leptospirosis. Cochrane Database of Systematic Reviews, 2025(7).
https://doi.org/10.1002/14651858.CD014935.pub2
Background
Leptospirosis is a bacterial disease caused by Leptospira spp, a zoonotic pathogen spread via contaminated soil and water. Corticosteroids have been used for the treatment or prevention of severe manifestations of disease, but the indications for their use and treatment efficacy remain uncertain. This review evaluates the existing evidence for the use of corticosteroids in leptospirosis from randomised trials.
